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PCOS · 5 min read

Metformin for PCOS explained

Metformin is commonly prescribed for PCOS, but what does it actually do? Here's how it works, who it's for, and what to expect.

Dr Susan WhitlockUpdated July 2026
Medically reviewed by Dr Susan Whitlock, AHPRA-registered GP — Last reviewed July 2026
Metformin for PCOS explained

What is metformin?

Metformin is a medication originally developed for type 2 diabetes that improves how your body responds to insulin. Because insulin resistance plays a central role in PCOS for many women, metformin is often prescribed off-label to help manage PCOS symptoms.

It can help with cycle regularity, weight management, and may improve ovulation in women trying to conceive. However, it's not effective for everyone and is usually part of a broader treatment plan.

What to expect

Metformin is usually started at a low dose and gradually increased to minimise side effects. The most common side effects are gastrointestinal — nausea, diarrhoea, and stomach discomfort. These often improve over time and are reduced by taking the medication with food.

It can take a few months to see the full benefits. Your GP will monitor your response and may arrange blood tests to check how your body is responding.

Is it right for you?

Metformin isn't necessary for every woman with PCOS. It's most helpful for women who have insulin resistance, difficulty losing weight, or irregular cycles. It's also sometimes used in fertility treatment to help improve ovulation.

Your GP can discuss whether metformin is appropriate for your individual situation, alongside other treatment options like the pill, lifestyle changes, and fertility planning.

Related condition

PCOS

References & sources

This content is general information and not a substitute for individual medical advice. Please consult a GP for your personal situation.

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